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doi: 10.1073/pnas.0704908104 179 NoelkerCMorelLLescotTOsterlohAAlvarez-FischerDBreloerMet al

The same group subsequently reported that BPC-157 modulates vasomotor tone by enhancing phosphorylation of Src, caveolin-1, and eNOS, and that the peptide reduces caveolin-1/eNOS binding a step that releases eNOS from caveolar inhibition and permits nitric oxide generation (Hsieh et al., 2020)

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Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

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The peroxidation of cell membrane lipids, triggered by iron and the inactivation of antioxidant pathways, results in the accumulation of lipid peroxides and reactive oxygen species (ROS), causing cell membrane rupture and cell death