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Furthermore, the Nrf2/ARE pathway, which controls redox homeostasis, is essential for preventing ferroptosis in cells

Received 2022-9-19

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In PCOS, SIRT3 deficiency may induce abnormal activation of the Phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) signaling pathway via mitochondrial oxidative stress, disrupting insulin-dependent glucose metabolism [81]

Burk RF, Norsworthy BK, Hill KE, Motley AK, Byrne DW

That question is unresolved