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Scheller HV Deciphering Triterpenoid Saponin Biosynthesis by Leveraging Transcriptome Response to Methyl Jasmonate Elicitation in Saponaria Vaccaria

Abbreviations Author Contributions Writingoriginal draft: R.S., S.S

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A Mutation in P62 Protein (p

The sgRNAs for glutathione synthetase (GSS), which regulates the second step of glutathione biosynthesis (53, 54), were also significantly depleted in the CRISPR screen, but only in the cultures grown in 8M of LCS3

Replacement is by either the salvage pathway, or more prominently, by de novo synthesis