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Both zinc deficiency (due to dietary insufficiency, malabsorption, or physiological stress) and zinc excess (from environmental pollution or feed oversupplementation) adversely affect health, disrupting mineral balance, enzyme function, and gut microbiota

These are usually sensory effects (burning, freezing, electroshock-like)

As a general rule, if youre going to use agarose beads once and then discard them, then regular (non-crosslinked) beads will work fine