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In vivo studies confirmed trans-epithelial and axonal transport of nanoparticles, with intranasal administration achieving substantially elevated MEL brain concentrations compared to intravenous or oral delivery

doi: 10.3945/jn.114.202093

Azurity Pharmaceuticals, Inc

Since many pathologic and toxic conditions result in sustained increase in cytosolic free Ca 2+ , which can lead to activation of CMK and phosphorylation of GCLC, theoretically, inhibition of GCL may further contribute to toxicity under these conditions

Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells

222 [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted] NIH (National Institutes of Health)