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Mutations of this gene were found in 11% of patients with autosomal recessive peripheral neuropathy, and in 76% of patients with axonal neuropathy plus neuromyotonia (92

Shiitake mushrooms and fermented foods, like tempeh, natto, and sauerkraut can contain some vitamin B12

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The addition of the N-terminal tyrosine residue was incorporated to facilitate radiolabelling for pharmacokinetic research studies, and has since become a standard part of the compounds structure as used in laboratory research
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