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doi: 10.1002/mrm.27702

Among approved drugs, participation of patients over 65 has ranged from 10 percent in 2014 to 39.9 percent in 2020, indicating a consistent increase in the share of elderly participants in trials resulting in FDA approval during this period (2021 data are yet incomplete)

The first major hurdle that became apparent shortly after the first IGF-1 assay was the discovery of IGFBPs, the presence of which significantly reduced the levels of immunoreactive IGF-1 in samples leading to misleadingly low results

Repurposing existing anti-inflammatory and metabolic drugs may be a viable approach to treat pain and metabolic dysfunction in PCOS

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