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This is particularly relevant for patients with metabolic syndrome where mitochondrial dysfunction is part of the disease mechanism

Anecdotally, benzyl alcohol also has a mild local anesthetic effect

Contamination can occur if the water is exposed to air or dust particles, so it should be kept in its original container and tightly sealed when not in use

The underlying clinical question has not changed

Systemic and intranasal ketorolac is contraindicated in labor and obstetric delivery because it may adversely affect fetal circulation and uterine contractions (2,3,5)

When present, side effects are typically mild and may include vivid dreams or altered sleep architecture as the brain undergoes increased neuroplastic activity, mild headaches during initial therapy (often resolving within days), temporary changes in appetite, or subtle mood variations during the adaptation period