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doi: 10.1016/j.chembiol.2020.03.011 89 SunXNiuXChenRHeWChenDKangRet al
Generally, two factors determine the behavior in this paradigm: The first is a positive exploratory drive originating from the nature of rodents to explore new environments (for food and shelter), and the second is the animal nature of avoiding open and brightly lit spaces (exposure to predators)

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Hox-driven conditional immortalization of myeloid and lymphoid progenitors: Uses, advantages, and future potential

On the other hand, additional observations have suggested that IDH-mutant AMLs are sensitive to treatment with BCL-2 inhibitors and to the differentiative induction with all-trans retinoic acid
Conclusion Recent studies showed a strong association between oxidative stress and apoptosis in animal models as well as in SLE patients