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Additionally, SFN combined with 5-aza-2-deoxycytidine and trichostatin A significantly reduced the CpG methylation levels in the NRF2 promoter region and inhibited the protein expression of DNA methyltransferase 1 (DNMT1), thereby promoting NRF2 expression, which may play a preventive role in colon cancer [151]
On the other hand, current therapeutic option for specific molecular targeting of neurodegenerative disorders are few and costly

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On the contrary, regulatory T cells (Tregs) drive ferroptosis by promoting the secretion of antioxidant thioxygen-1 (Trx-1) (Mougiakakos et al., 2011)

Gorshkov A, Purvinsh L, Brodskaia A, Vasin A (2022) Exosomes as natural nanocarriers for RNA-based therapy and prophylaxis

It usually depends on what the experts suggest you do and what kind of needs your body has
