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Similarly, there is a compelling need to evaluate toxicity in more clinically relevant model systems, including primary culture of airway and alveolar epithelium and in vivo animal models that combine e-cig exposure with clinically relevant bacterial and viral infections

De Tata, V

This state of weakened adrenal function can disrupt energy production, compromise immunity, and even interfere with nervous system function

Fe and Fe-associated metabolite levels in spent media corroborate an Fe-replete condition Having observed transcriptional signatures of an Fe-replete state during sulfur starvation, we next quantified extracellular Fe using ICP-OES

Indeed, it has been demonstrated in experimental animal models, the deficiency of Cu could lead to hypertrophic cardiomyopathy

In this case the C2 of lactate is oxidized from alcohol to ketone
