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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Karakas E., Wilson H.L., Graf T.N., Xiang S., Jaramillo-Busquets S., Rajagopalan K.V., Kisker C

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Additionally, it promotes the expression of tumor-suppressor miRNAs ( miR-34a , miR-126 , and miR-let7b ) and enhances the gene levels of Caspase-9 , p53 , APAF1 , and Bax [952, 955]

Collectively, these results suggested that APR-017 and LCS3 treatment induce vulnerability of VRK2-deficient PC cells by GSH inhibition and consequent disruption of the balance between ROS generation and antioxidation

[DOI] [PMC free article] [PubMed] [Google Scholar] 911.Union A.o.w.o.t.E

The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes