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Intranasal transplantation of human NSCs into APP/PS1 mice results in their differentiation into cholinergic neurons, reducing A accumulation and ultimately alleviating cognitive dysfunction (Lu et al., 2021)

2.5 Statistical analysis Data are presented as mean standard deviation (SD)

Meanwhile, excess iron could increase matrix metalloproteinases (MMPs) expression induced by IL- 1 [117]

Future developments may focus on enhanced recyclability and further energy optimization

These metabolites exhibit distinct pharmacological properties compared to parent THC, with 11-OH-THC reported to be more potent than THC, while THC-COOH is considered inactive but is often used as a plasma marker of cannabis consumption in drug tests [51,88]

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