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This may lead to underestimations of CAR levels and overestimations of levels of B-ALA and HIS [20]

Notably, 4-HNE can activate the PPAR pathway, suppressing PGC-1-mediated mitochondrial biogenesis and reducing local ATP supply at synapses, thereby impairing plasticity mechanisms such as LTP (194)

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Concord, NH: Fritz Perlberg Publishing

The combination of dietary intervention (ovo-lacto vegetarian diet intervention including SCFAs for 14 days) and bowel cleansing (faecal enema for 8 days) was evaluated in a small group (N = 10) of PD patients [94]

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