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H., and Sim S
The brain tissue of PD patients is typically characterized by the death of dopaminergic, neuromelanin-containing neurons in the area of locus coeruleus and substantia nigra
Therefore, comparative analysis of the molecular pathways of tumorigenesis of the two cancer types can provide insight into prognosis strategies
In addition to redox homeostasis, SOD1 plays a critical role on intracellular copper buffering 128
Simultaneously, copper overload can impair the cellular antioxidant defense system, exacerbating oxidative injury (123-125)
40 The orexin system also regulates stress and has been identified as a potential brain circuit in the treatment of AUD, especially given the sleep cycle disruptions seen in patients with AUD
