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They are: Contaminated or mislabelled compounded products research-grade vs pharmaceutical-grade manufacturing matters enormously Incorrect dosing without clinical oversight, patients routinely underdose (no effect) or overdose (unknown risk) Drug interactions particularly relevant if you are on GLP-1 therapy, immunosuppressants, or anti-inflammatory medications

The hydroxyl radical is more reactive than the superoxide anion, thus producing greater tissue damage

Clauw DJ, Essex MN, Pitman V, Jones KD

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