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Using a cecal ligation and puncture (CLP) murine model, in vitro microglia-neuron co-cultures, data-independent acquisition (DIA) proteomics and liquid chromatography-mass spectrometry (LC-MS) metabolomics, SAE neuropathology and phenotypes were characterized

Environmental Protection Agency (EPA) has not formally established an oral reference dose for copper or a maximum acceptable dose for inclusion in its Integrated Risk Information System database (120)

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The study demonstrated the dose-dependent antihistaminic and anti-edematous effects of quercetin phospholipids supplementation and highlighted its safety, suggesting potential applications in conditions linked to histamine release and oedema [76]