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Data analysis MS raw files were searched against the Swissprot mouse database downloaded 25 May 2022 using the Comet search algorithm 77 implemented in GFY Core software from Harvard

Statistical significance was determined using a Students t -test or non-parametric MannWhitney or Wilcoxon signed-rank test for two-group comparisons

Access this article Similar content being viewed by others Data availability The corresponding author will provide the datasets created during and/or analyzed during the current investigation upon reasonable request

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Before the experiment began, all animals underwent a one-week acclimatization period to allow adaptation to the laboratory environment