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Autologous HSCT should be considered as the first choice for eligible patients achieving second molecular remission (undetectable MRD in the BM).7,108,109 However, a recent report questions the role of transplantation, at least in patients achieving molecular remission with ATO and ATRA who do not have CNS disease at relapse and who have received a full course of consolidation with ATO.33 Chakrabarty et al.110 reported on 294 patients who received either allogeneic transplant (n = 232) or autologous transplant (n = 62) between 1995 and 2006

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It is found mainly in animal sources such as meat, milk, egg, fish, and shellfish, explaining why strict vegetarians are highly prone to developing vitamin B 12 deficiency [67]

2 ) in the vascular endothelium COX-2 also serves an important constituitive housekeeping role for normal renal development and maintenance of renal physiology

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The potential synergies between MSM and glutathione