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According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Higashikuni Y., Sainz J., Nakamura K., Takaoka M., Enomoto S., Iwata H., Tanaka K., Sahara M., Hirata Y., Nagai R., et al

If left untreated, severe hypoglycemia can lead to loss of consciousness, seizures, and even death

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This can be a drawback for some users, as it may be inconvenient to administer the peptide multiple times a day
