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1 Introduction Autoimmune diseases (ADs) arise from the immune systems aberrant response against self-tissues, encompassing diverse conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), type 1 diabetes (T1D), and primary biliary cholangitis (PBC) ( Mounting evidence suggests that gut microbiota and its metabolites play a key role in host health and diverse diseases, such as obesity, depression, sclerosis, kidney disease, and dialysis ( At present, in the interest of reshaping the disordered intestinal immune activity in the disease state and alleviating the disease, people propose a series of flora-related immunotherapies based on the close interaction between the intestinal immune system and the flora ( Clostridium , a genus of anaerobic, Gram-positive, thick-walled bacteria, constitutes a dominant component of the healthy gut microbiota ( Clostridium species may confer clinical benefits across multiple ADs ( 2 Classification and sources of Clostridium as probiotics The intestinal clostridia as probiotics mainly contain Clostridium butyricum ( CB ), Faecalibacterium prausnitzii ( FP ), Clostridium cocleatum , etc

Promotes healthy red blood cell production and helps prevent anaemia

The Drugs@FDA database contains no entry for BPC-157 in any indication, and ClinicalTrials.gov shows no ongoing human studies registered in the United States

A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes

The cost of a single vitamin B12 injection dose is 50 (per IM injection)

The copper component of GHK-Cu contributes directly to angiogenic processes by serving as an essential cofactor for lysyl oxidase and other enzymes involved in ECM cross-linking required for vessel maturation and stability