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The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug
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They demonstrated that miR-365-3p/ETS homologous factor (EHF, a KRT16transcription factor) axis could reduce OSCC cell migration, invasion, metastasis, and chemoresistance to 5-fluorouracil through the suppression of KRT16
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