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In both experimental models and human diabetic subjects, there is an initial metabolic phase that is responsive to metabolic corrections [90,91]

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The actions of norepinephrine and epinephrine are exerted via receptor-mediated signal transduction events

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[Link] A mechanism for the antidepressant property of ALCAR is proposed, and the novelty of the possible role of ARTN in depression is suggested. Soczynska, J, et al, Acetyl-L-carnitine and -lipoic acid: possible neurotherapeutic agents for mood disorders? in Expert Opinions on Investigational Drugs , Volume 17, Issue 6, 2008, pp 827 - 843

ALA functions both as a coenzyme for mitochondrial enzymes and as an ideal antioxidant