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Nutrients 9 (9), 1021

Various BA transporters have been gradually found to be expressed in the CNS including MRP2, NTCP and BSEP in the choroid plexus [49], OATP in brain capillary endothelial cells [50], ASBT in the hypothalamus [51, 52], providing a mechanism for the neuronal uptake of conjugated BA from the periphery into the CNS by BA transporters

This effect is believed to come from B12s support of neurotransmitters such as serotonin and dopamine, which influence cognitive function and emotional balance

Nutt JG, Burchiel KJ, Comella CL, Jankovic J, Lang AE, Laws ER, Jr., et al

Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart

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