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First-pass hepatic metabolism degrades an unknown percentage of orally administered 5-Amino-1MQ before it reaches systemic circulation, introducing dosing variability that conflicts with controlled study design

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there is a higher proportional turnover of body fluid in infants compared to adults (it is estimated that the daily fluid intake and outgo, as a propotion of extracellular fluid, is in infancy twice that of an adult)

These results were consistent across intraperitoneal and local administration 3

We like to call them the black thumb hydrangea because they are so easy and reliable, they make even people who have no experience (or claim to have a black thumb, which we dont believe even exists, frankly) look like garden rock stars

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