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Description
Therapeutic modulation of epigenetic drivers of drug resistance in ovarian cancer

Inhibition of cGAS-STING or type I IFN restores DHODH expression, reverses lipid peroxidation and ROS production, and rescues Mn 2+ -induced ferroptosis in tumor cells (148)

ROS generation

[Lipid peroxidation and activity of diagnostically significant enzymes in cosmonauts after flights of various durations]

The C3 component can be either an aliphatic chain or part of a five- or six-membered oxygen-containing ring with C6 segments
Systemic injection into abdominal fat also provides benefits, though potentially less concentrated at the specific injury site