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References Abi-Ghanem C, Jonnalagadda D, Chun J, Kihara Y, Ranscht B (2022) CAQK, a peptide associating with extracellular matrix components targets sites of demyelinating injuries

2733, pubmed.ncbi.nlm.nih.gov/25559140/, Bruce, et al
This anti-inflammatory effect helps prevent the transition from acute injury to chronic kidney disease or heart failure, representing a critical therapeutic benefit beyond the immediate protection during the ischemic event itself
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Although it is rare, too much niacin from supplements could cause red skin, tingling in the face, arms and chest, and itching

The Journal of cell biology, 1994, 125(4): 929- 943