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In rat tendons, BPC-157 enhances collateralization and increases fibroblast density in vitro and in vivo studies

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doi: 10.3389/fncel.2022.889765

Its cytotoxic mode of action is mediated by its interaction with DNA to form DNA adducts, primarily intrastrand crosslink adducts, which activate several signal transduction pathways, including those involving ATR, p53, p73, and MAPK, and culminate in the activation of apoptosis

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