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doi: 10.1016/j.cell.2012.03.042 11 YangWSSriRamaratnamRWelschMEShimadaKSkoutaRViswanathanVSet al
Biopsychosoc Med

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As mentioned, BPC 157 may interfere with the early events (i.e., immediate application after lidocaine) [60]

Activation of NF-kB/Rel proteins therefore requires degradation of IkB proteins via ubiquitin-mediated proteolysis to initiate nuclear translocation and DNA binding of active NF-kB/Rel complexes [84]

These studies reveal the complex role of epigenetic regulation in OA ferroptosis and provide new potential intervention targets (Table 2)
