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225 Administration of the PRMT4 inhibitor TP-064 in a mouse model of atherosclerotic cardiovascular disease can induce a decrease in monocyte tumor necrosis factor- (TNF-) secretion, downregulate the gene expression of the glycogen metabolism-related protein G6pc in the liver, and reduce plasma triglyceride levels, exerting regulatory effects from inflammatory and metabolic pathways

ATRX is associated with alternative lengthening of telomeres as an additional mechanism for telomere maintenance in tumors lacking TERT promoter mutations (128)

Paine-Murrieta GD, Taylor CW, Curtis RA, Lopez MHA, Dorr RT, Johnson CS

Reduces free radicals formed in the body

Because the greatest vision problems for people with albinism occur during the early development of the eye, our eventual goal is to work with infants, said Brian Brooks, M.D., Ph.D., clinical director at NEI and lead author of the study