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This is supported in a study by Brignardello et al [214] that looked at gut permeability in asymptomatic, non-smoking obese volunteers and observed no differences compared to healthy controls

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Initially, the alterations in intracellular protein concentrations post-treatment were assessed, and the principal component analysis (PCA) outcomes demonstrated a notable divergence in protein expression between the D-CuP-treated group and the PBS-treated control group (Fig

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