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Rho kinase inhibition maintains intestinal and vascular barrier function by upregulation of occludin in experimental necrotizing enterocolitis

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These data clearly indicate an increase in circulating levels of specific chemokines and cytokines that are known to modulate systemic levels through immune cells, results in affecting local intestinal inflammation and tissue damage in IBD patients (304)

Additionally, high doses of folic acid (exceeding 0.1 mg per day) may result in hematologic remission in patients with vitamin B12 deficiency

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