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In detail, the last seven amino acids of the G s -5 helix connect with R139 3.50 , A142 3.53 , and I143 3.54 of TM3, L236 5.65 of TM5, K308 6.30 , A307 6.29 and R310 6.32 of TM6, and N374 8.47 at the TM7Helix8 hinge in CCK1R (Fig

Notably, TCM compound formulas remain understudied in this context, representing a critical avenue for future DN therapeutic development

*Based on usable volume

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Support for muscle function: The compound may help in the optimal function of muscles, contributing to greater physical activity

In addition, B12 deficiency-associated fatigue is often accompanied by other symptoms such as numbness and tingling, cognitive impairment (memory and concentration problems), mood swings (depression), skin changes (pale skin), shortness of breath, or fast heart rate