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Decreased mtDNA copy number downregulates PGC-1 and TFAM expression and eventually inhibits mitochondrial biogenesis (89)

They contain high levels of antioxidants, fatty acids, minerals, and vitamins

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Martini M., Ferrara A

Similarly, asthma patients receiving conventional therapy alongside six months of oral choline supplementation exhibited significant reductions in circulating eosinophils and factors involved in bronchial hyperreactivity, such as IL-5 and cysteinyl leukotrienes (Cys-LT) (94)

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