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Biochim Biophys Acta 377:251257, 1975

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Studies have shown that probiotics support gut barrier function, modulate immune response and reduce inflammation ( 3.1 Probiotics mechanism of action Through interaction with immune cells and epithelial cells, probiotics participate in the control of immunological response ( Figure 1 )

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Overview of Glutathione Function The pleiotropic functions of glutathione are mostly associated with the sulfhydryl (SH) group in the Cys residue [1,2]

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doi: 10.1016/j.vph.2018.02.010

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Mitochondrial reactive oxygen species (ROS) act as a key regulator, promoting RIPK1 autophosphorylation, which in turn enhances necrosome assembly and MLKL pore-forming capacity, ultimately driving necroptosis (32)

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Nunn et al., 2020)

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