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When you take Vitamin B12 through an intramuscular injection, you can process 100% of that vitamin, whereas with an oral supplement, usually only about 50-70% of the vitamin is able to be processed and metabolized

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

Tsukamoto and Lu 2001

Finally, propionyl-CoA is converted to propionic acid with the release of CoA by a CoA-transferase [74,88,98,118,189,201]

In conclusion, curcumins broad-spectrum therapeutic effects, including its ability to mitigate cytokine storms, inhibit viral infections, and reduce thrombotic complications, position it as a promising natural compound for managing COVID-19 and its associated complications

Acknowledgements The authors would like to extend their appreciation to the Deanship of Scientific Research, King Saud University for funding through Vice Deanship of Scientific Research Chairs