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The PEACE-6 trial is randomizing patients with de novo or metachronous mHSPC, focusing on therapy de-escalation for good responders (undetectable PSA at 68 months) and treatment intensification for poor responders

1 Vitamin D exerts its biological actions through vitamin D receptors and hence plays its role through the regulation of gene expression in places where its receptors exist, such as the endocrine system

On the other hand, FTO maintains cellular glucose uptake and stabilizes glycolysis

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Cytoskeletal architecture and migration mechanisms. Nat Rev Mol Cell Biol

the variability may be higher or lower in other regions of the brain
