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If you get digestive symptoms after taking B12, often there is a bacterial overgrowth or possibly fungal overgrowth creating the digestive symptoms
However, by consuming various B12 sources you can achieve the recommended daily intake without trouble

Eur J Pharm Sci

Most serums dilute their active compounds across 20 or 30 other components
Improved nerve health: NAD+ repairs DNA, while B12 protects nerves