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In a prospectively evaluated patient cohort with PSC, elevated serum soluble (s)VAP-1 levels predicted poorer transplant-free survival for patients, independently (HR: 3.85, p=0.003) and additively (HR: 2.02, p=0.012) of the presence of liver cirrhosis

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However, studies using various single-cell RNA-sequencing methods optimized for the ENS are now emerging, allowing for extensive gene expression profiling of functional molecular constituents of enteric neurons such as ion channels, transmitters and their synthesizing enzymes, as well as receptors [35, 36]

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Statistics Data represent mean SEM of all experiments