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On the other hand, tamoxifen may function as an agonist in the transcription of genes where the AF-1 domain, instead of AF-2 plays a critical role in transcription (McGuire et al ., 1977

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The term IGF1 includes the recombinant form of IGF1

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The guanidyl group of Arg132 helps stabilize the pentavalent transition state that yields the acyl-phosphate intermediate

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