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Autophagy protects mitochondrial health in heart failure

Mechanistically, Arctigenin downregulated CPT1-mediated FAO, which further inhibited nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome assemblies in macrophages (Qiao et al., 2020)

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This analysis showed that while autophagy-proficient green cells competed to migrate and started to sprout, ATG5-compromised red cells remained encapsulated in the spheroids core (Fig