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The clinical trial data is specifically reassuring on this point: across six trials involving approximately 900 participants, glucose levels, insulin levels, and markers of insulin sensitivity remained unchanged from baseline
Everything the B12 injection does, plus fat metabolism support, liver function optimization, and insulin sensitization

So, inhibiting GOAT could impede the production of acyl-ghrelin and increase desacyl-ghrelin, thus improving glucose homeostasis

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While these data formed the basis of early enthusiasm, later peptide clinical trials showed that such results did not translate meaningfully into clinical efficacy

Crosses the blood brain barrier to participate in methylation reactions in the brain
