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Hepatic safety profiles of emerging systemic therapies Deucravacitinib has demonstrated a favorable hepatic safety profile across multiple clinical trials, with ALT and AST elevations being generally mild, transient, and often related to underlying liver conditions or concomitant medications (Lebwohl et al

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In their study, curcumin conferred significant protection to Fe 2+ andCu 2 -mediated damage with IC 50 (M) at o 6.2 0.2 and 30.8 0.6, respectively [287]

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Zhang Y, Tan H, Daniels JD, Zandkarimi F, Liu H, Brown LM, Uchida K, OConnor OA, Stockwell BR: Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model