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These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue. Sodium and chloride ions screen the peptides positive charge, so the receptor sees less of it and the welt shrinks

Zinc intestinal barrier anti-inflammatory pathway: human RCTs (252) demonstrate that zinc supplementation (20 mg/day) upregulates the expression of intestinal tight junction proteins (e.g., occludin) and reduces systemic inflammation

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doi: 10.1016/s0006-2952(03)00012-1

Astrocytic and neuronal apolipoprotein E isoforms differentially affect neuronal excitability

A study by Sagara et al (126) investigated the effects of soy protein and isoflavones on blood pressure in 61 high-risk (SBP of 130 mmHg or greater) middle-aged Scottish men