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A body of literature has demonstrated that inflammatory cytokines activate many of the molecular pathways involved in skeletal muscle wasting, leading to an imbalance between protein synthesis and degradation [4,5]

Misheva M, Kotzamanis K, Davies LC, Tyrrell VJ, Rodrigues P, Benavides GA, Hinz C, Murphy RC, Kennedy P, Taylor PR, Rosas M, Jones SA, Mclaren JE, Deshpande S, Andrews R, Schebb NH, Czubala MA, Gurney M, Aldrovandi M, Meckelmann SW, Ghazal P, Darley-Usmar V, White DA, ODonnell VB

doi: 10.1007/s11064-023-04000-z 2

Int J Syst Bacteriol 49, 787794 10.1099/00207713-49-2-787

It depends on the impaction of a gallstone in the cystic duct or or the Hartmanns pouch leading to compression and obstruction of the common hepatic duct or common bile duct [183] and obstructive jaundice
