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The presence of lectins, -glucans, polyphenols, p -hydroxybenzoic acid, protocatechuic acid, agllic acid, cinnamic acid, p -coumaric acid, ferulic acid, chlorogenic acid, and catechin in mushrooms improves hyperglycemia by regulating insulin and glucagon secretion [149,150,151]

Interestingly, a role for UCP2 in the transport of mGSH has been described in neurons, suggesting that the transport of protons back into the matrix by UCP2 may favor the movement of GSH (de Bilbao et al., 2004)

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Mol Cell Biol 24:18441854 Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Ostman A (2014) The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation

DISCLOSURES: The authors declare no conflicts of interest relevant to the content of this article

El-Kady et al., 2022)