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5.4 Glioblastoma The therapeutic application of curcumin in glioblastoma (GBM) has been significantly limited by its poor bioavailability and solubility, as well as the restrictive blood-brain barrier (BBB) [201]

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When these electrons are transferred through the mitochondrial electron transport chain via oxidative phosphorylation, they yield approximately 2 to 3 ATP per electron pair

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In keeping with the longevity of their role, M2 macrophages independently stimulated with IL4, signal transducer and activator of transcription 6 (STAT6) and PPAR-coactivator-1 (PGC-1) engage an anti-inflammatory phenotype and rely on fatty acid oxidation (FAO) to generate ATP (42)

Abstract Introduction: Multifactorial Eye disorders are a significant public health concern and have a huge impact on quality of life