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Gastroenterology 164 , 619629 (2023)

In line with heightened FOXO3A and MT2 activity, mice treated with -hydroxybutyrate exhibited significant protection against OS [Shimazu et al ., 2013]

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Askanaz Ji, Carpentier YA, Michelsen CB, Elwyn DH, Furst P, Kantrowitz LR, Gump FE, Kinney JM: Muscle and plasma amino acids following injury: influence of intercurrent infection

Among several AKR inhibitors tested against AKR1B15, only JF0064 significantly inhibited AKR1B15 while potent inhibitors of AKR1B1 and AKR1B10 such as tolrestat, epalrestat, sulindac, and sorbinil failed to inhibit AKR1B15