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These pathways include the cyst(e)ine/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis 1,4 , the ferroptosis suppressor protein 1 (FSP1)/coenzyme Q 10 (CoQ 10 ) axis on the plasma membrane 5,6 , the guanosine triphosphate cyclohydrolase 1 (GCH1)/tetrahydrobiopterin (BH4)/dihydrofolate reductase (DHFR) axis 7,8 , and the mitochondrial dihydroorotate dehydrogenase (DHODH)/CoQ system 9

[DOI] [PubMed] [Google Scholar] 15.Yu B.J., Oz R.S., Sethi S

They are experiments done in a laboratory or on laboratory animals, not in human beings

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doi 10.2174/1871530322666220407002936