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Apart from possible selenosis caused by excessive Se accumulation, intervention with micronutrient Se in subjects with adequate Se levels failed to reduce the incidence of thyroid cancer (82)

doi: 10.1080/07315724.2004.10719428 511 Ceballos-SnchezDCasanova-CrespoSRodrguez-LagunasMJCastellMMassot-CladeraMPrez-CanoFJ

Thus, transparent riskbenefit communication is vital to avoid consumer backlash (230233)

and Brown, C

Antioxidant, anti-inflammatory, anti-menopausal, and anti-cancer effects of lignans and their metabolites

Evidence from an animal model also shows that AGEs can induce insulin resistance by repressing the skeletal muscle glucose transporter GLUT4 [108]